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Total synthesis of clavulones

โœ Scribed by Masakatsu Shibasaki; Yuji Ogawa


Book ID
104222456
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
238 KB
Volume
26
Category
Article
ISSN
0040-4039

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A halogenated clavulone analog 1 which has remarkable antitumor activity was synthesized in a stereoselective and enantioselective manner. We have described the structures of novel marine prostanoids clavulone I, II, III, IV and their congecers, which are noted by their strong antitumor activity, is