A new total synthesis of (±)-clavulanic
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Peter H. Bentley; Gerald Brooks; Martin L. Gilpin; Eric Hunt
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Article
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1979
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Elsevier Science
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French
⚖ 128 KB
Regioselective reactions at the terminal double bond of the racemic azetidinone dienylether (4), provides a source of clavulanic acid and several analogues. We have recently reported la the first total synthesis of (t)-olavulenic acid (l), which relied upon the construction, double-bond isomerisati