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Total synthesis of both enantiomers of trans-2,3-cis-3,4-dihydroxyproline

✍ Scribed by Franca Zanardi; Lucia Battistini; Marika Nespi; Gloria Rassu; Pietro Spanu; Mara Cornia; Giovanni Casiraghi


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
808 KB
Volume
7
Category
Article
ISSN
0957-4166

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Chemoenzymatic synthesis of both enantio
✍ Ayhan S. Demir; Asuman Aybey; Γ–zge Sesenoglu; Fatos Polat πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 135 KB

4-Oxo-3,4-dihydro-2-chromen-3-yl acetate is synthesized using manganese(III)acetate starting from 2,3-dihydro-4Hchromen-4-one. K 2 CO 3 mediated hydrolysis of 4-oxo-3,4-dihdro-2-chromen-3-yl acetate furnished 3-hydroxy-2,3-dihydro-4Hchromen-4-one in high yield.The enantioselective hydrolysis of (Β±)-