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Total synthesis of an enzyme. III. Synthesis of a protected hexacontapeptide corresponding to the 65-124 sequence of ribonuclease A

โœ Scribed by Jenkins, Susan R.


Book ID
127373043
Publisher
American Chemical Society
Year
1969
Tongue
English
Weight
259 KB
Volume
91
Category
Article
ISSN
0002-7863

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Studies on polypeptides. XXXV. Synthesis
โœ P. Hoogerhout; Cecile Schattenkerk; K. E. T. Kerling ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 249 KB

## Abstract The partially protected heptapeptide, Bocโ€”Asp(OtBu)โ€”Serโ€”Serโ€Thrโ€Serโ€Alaโ€Alaโ€OH, corresponding to the sequence 14โ€20 of bovine pancreatic ribonuclease, was prepared by a combination of solidโ€phase synthesis using N^ฮฑ^โ€(9โ€fluorenylmethoxycarbonyl) amino acids and synthesis in solution by