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Total Synthesis of Ageladine A, an Angiogenesis Inhibitor for the Marine Sponge Agelas nakamurai.

✍ Scribed by Matthew L. Meketa; Steven M. Weinreb


Publisher
John Wiley and Sons
Year
2006
Weight
9 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract Two stereoisomers of penazetidine A (1a), the azetidine alkaloid isolated from the Indo‐Pacific marine sponge __Penares sollasi__, were synthesized by starting from (__S__)‐serine and (__R__)‐or (__S__)‐citronellol. The natural penazetidine A must be either (2__S__,3__R__,4__S__,12β€²__R_