Total Synthesis of (2 S ,3 S ,5 S ,10 S )- 6,9-Epoxynonadec-18-ene-7,10-diol and Formal Total Synthesis of (+)- trans -Kumausyne from d -Arabinose
β Scribed by Gadikota, Rajendrakumar Reddy; Callam, Christopher S.; Lowary, Todd L.
- Book ID
- 126418468
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 106 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0022-3263
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Enantiocontrolled Construction of Functionalized Tetrahydrofurans: Total Synthesis of (6S,7S,9R,10R)-6,9-Epoxynonadec-18-ene-7,10diol, a Marine Natural Product. -A new strategy for the construction of highly functionalized tetrahydrofurans via the key bis-C 3 building block (III) is developed and ap
The stereocontrolled synthesis of (6S,7S,9R, 10R)-6,9-epoxynonadec-18-ene-7,10-diol, isolated from the brown alga, Notheia anomala, has been achieved. The key 2,3,5-trisubstituted tetrahydrofuran ring was constructed by alkylation of the sulfonyl-stabilized oxiranly anion followed by 5-endo cyclizat
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