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Total Synthesis of 10-Deoxymethynolide and Narbonolide

โœ Scribed by Xuan, Richeng; Oh, Hong-Se; Lee, Younghoon; Kang, Han-Young


Book ID
120851448
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
196 KB
Volume
73
Category
Article
ISSN
0022-3263

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ChemInform Abstract: Total Synthesis of
โœ Ronaldo A. Pilli; Carlos Kleber Z. de Andrade; Carlos Roberto O. Souto; Armin de ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

Total Synthesis of 10-Deoxymethynolide, the Aglycon of the Macrolide Antibiotic 10-Deoxymethymycin. -The title compound (XI) is prepared in 12% overall yield via a synthetic equivalent (VIII) of the Prelog-Djerassi lactonic acid and the construction of a 12-membered lactone through an intramolecula