ChemInform Abstract: Total Synthesis of 10-Deoxymethynolide, the Aglycon of the Macrolide Antibiotic 10-Deoxymethymycin.
β Scribed by Ronaldo A. Pilli; Carlos Kleber Z. de Andrade; Carlos Roberto O. Souto; Armin de Meijere
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Total Synthesis of 10-Deoxymethynolide, the Aglycon of the Macrolide Antibiotic 10-Deoxymethymycin.
-The title compound (XI) is prepared in 12% overall yield via a synthetic equivalent (VIII) of the Prelog-Djerassi lactonic acid and the construction of a 12-membered lactone through an intramolecular Nozaki-Hiyama-Kishi coupling reaction. -(PILLI,
π SIMILAR VOLUMES
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