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Total Synthesis and Conformational Analysis of the Antifungal Agent (-)-PF1163B.

โœ Scribed by Fodil Bouazza; Brigitte Renoux; Christian Bachmann; Jean-Pierre Gesson


Publisher
John Wiley and Sons
Year
2004
Weight
60 KB
Volume
35
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Total Synthesis of
โœ A. G. M. BARRETT; K. KASDORF ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 26 KB ๐Ÿ‘ 1 views

Total Synthesis of the Pentacyclopropane Antifungal Agent FR-900848. -Starting with asymmetric cyclopropanation reactions the corresponding fatty acid is built up. It is coupled with the nucleoside amine to yield the title compound (I), identical with the natural product. -(BARRETT, A.