The Laulimalide Family: Total Synthesis
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Andreas Gollner; Karl-Heinz Altmann; JΓΌrg Gertsch; Johann Mulzer
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Article
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2009
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John Wiley and Sons
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English
β 516 KB
## Abstract **A sensitive family**: The first total synthesis of the antitumor agents neolaulimalide and isolaulimalide as well as a highly efficient route to laulimalide is described. A Kulinkovich reaction followed by a cyclopropylβallyl rearrangement is used to install the __exo__βmethylene grou