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Total Synthesis and Antileishmanial Activity of the Natural Occurring Acetylenic Fatty Acids 6-Heptadecynoic Acid and 6-Icosynoic Acid

✍ Scribed by Néstor M. Carballeira; Michelle M. Cartagena; Christopher Fernández Prada; Celia Fernández Rubio; Rafael Balaña-Fouce

Book ID
107488115
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
641 KB
Volume
44
Category
Article
ISSN
0024-4201

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## Abstract The antifungal, naturally occurring acetylenic fatty acid 6‐nonadecynoic acid was synthesized in three steps (18 % overall yield), for the first time starting with commercially available 1‐tetradecyne. The synthesis developed herein will facilitate the further study of the antifungal pr