Total synthesis and absolute configuration of bengamide A
β Scribed by Chida, Noritaka; Tobe, Takahiko; Okada, Shinsuke; Ogawa, Seiichiro
- Book ID
- 121268704
- Publisher
- The Royal Society of Chemistry
- Year
- 1992
- Tongue
- English
- Weight
- 295 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0022-4936
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A total synthesis of bengamide E is reported. The synthesis includes the utilization of D-tartrate as the chiral building block, construction of the E-olefin by the Julia protocol, an anti-aldol reaction to generate C-2 and C-3 stereocenters, and coupling of the thioester with caprolactam hydrochlor