Total Syntheses of Zaragozic Acids A and C by a Carbonyl Ylide Cycloaddition Strategy.
β Scribed by Yuuki Hirata; Seiichi Nakamura; Nobuhide Watanabe; Osamu Kataoka; Takahiro Kurosaki; Masahiro Anada; Shinji Kitagaki; Motoo Shiro; Shunichi Hashimoto
- Publisher
- John Wiley and Sons
- Year
- 2007
- Weight
- 17 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The zaragozic acids and squalestatins, a novel family of fungal metabolites isolated and characterized by researchers at Merck [1] and Glaxo, [2] respectively, in 1992, are the most potent inhibitors of squalene synthase known to date. [3] Some members of this family have also demonstrated the abili
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract A unified synthetic strategy for the asymmetric syntheses of the natural products diversonol and lachnoneβ C was developed by using the domino vinylogous aldolβoxaβMichael reaction as the enantioselective key step. Further transformations include dihydroxylation, lactolβopening by a Witt