Total Deprotection of N,N'-Bis(tert-butoxycarbonyl)guanidines Using SnCl 4 . -An excess of SnCl 4 is found to be effective for the high yielding total deprotection of bis-Boc guanidines (I) (11 examples). -
Total deprotection of N,N′-bis(tert-butoxycarbonyl)guanidines using SnCl4
✍ Scribed by Hugues Miel; Sylvain Rault
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 132 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The total dewotection of N~Ubis-Boc guanidines using SnCI4 woceeds smoothly in ethyl acetate at room tempemtme and leads to the easily isolable cone~n~g guanidinlum chlorides.
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