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Total and free quinidine by fluorescence polarization immunoassay and comparison with high performance liquid chromatography

✍ Scribed by Bai Hsiun Chen; E.Howard Taylor; Eleanor Kennedy; Bruce Ackerman; Keith Olsen; Alex A. Pappas

Book ID
115826035
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
109 KB
Volume
175
Category
Article
ISSN
0009-8981

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πŸ“œ SIMILAR VOLUMES

Comparison of high pressure liquid chrom
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High pressure liquid chromatography (HPLC) and fluorescence polarization immunoassay (FPIA) were compared in a quinidine pharmacokinetic study. Six healthy male subjects received single oral doses of regular release (RR) quinidine sulfate, sustained release (SR) quinidine bisulfate and the same dose

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Hydroquinidine is a structural analogue of quinidine. It is used in the treatment and prevention of cardiac arrhythmias and necessitates serum monitoring. Fluorescence polarization immunoassay (FPIA) of quinidine has been proposed and we have tested the performance of this assay for hydroquinidine u