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Topological structure of closed circular DNA

✍ Scribed by Wenyuan Qiu; Houwen Xin

Book ID: 114142719
Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 372 KB
Volume: 428
Category: Article
ISSN: 0166-1280
DOI: 10.1016/s0166-1280(97)00255-8

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A closed-circular DNA duplex, especially a plasmid, for example, is known to have a n interwound right-handed (negative sense by definition) superhelical structure when it is isolated "intact" from a living cell.' Such a superhelical structure is considered to involve appreciable alterations in DNA