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Topically Active Carbonic Anhydrase Inhibitors for Glaucoma

โœ Scribed by Podos, Steven M.

Book ID
121300558
Publisher
American Medical Association
Year
1991
Tongue
English
Weight
379 KB
Volume
109
Category
Article
ISSN
0003-9950

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๐Ÿ“œ SIMILAR VOLUMES

Topically active carbonic anhydrase inhi
Topically active carbonic anhydrase inhibitors. 3. Benzofuran- and indole-2-sulfonamides
โœ Graham, Samuel L.; Hoffman, Jacob M.; Gautheron, Pierre; Michelson, Stuart R.; S ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› American Chemical Society ๐ŸŒ English โš– 857 KB

Derivatives of benzofuran-and indole-2-sulfonamide were prepared for evaluation as topically active ocular hypotensive agents. These compounds were found to be excellent inhibitors of carbonic anhydrase and to lower intraocular prmure in a rabbit model of ocular hypertension. However, the developmen