Toll-like receptors 4 induces expression of matrix metalloproteinase-9 in human aortic smooth muscle cells
β Scribed by Hongli Li; Hao Xu; Shaowen Liu
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 218 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0301-4851
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Endotoxemia by bacterial lipopolysaccharide (LPS) has been reported to affect gut motility specifically depending on Tollβlike receptor 4 activation (TLR4). However, the direct impact of LPS ligation to TLR4 on human smooth muscle cells (HSMC) activity still remains to be elucidated. Th
Citrus fruits are high in naringin, which has a beneficial effect on cardiovascular diseases. However, the matrix metalloproteinase-9 (MMP-9) regulation involved in cell migration and invasion remains to be identified. Naringin inhibited tumor necrosis factor-alpha (TNF-alpha)-induced expression of
## Abstract The expression of matrix metalloproteinaseβ9 (MMPβ9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMPβ9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor