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Mechanisms of increased expression of toll-like receptor-4 in human monocyte/macrophage-derived foam cells

โœ Scribed by Cheng Bei; Yu Qizhen; Bai Zhifeng; Ke Li; He Ping

Publisher
Springer-Verlag
Year
2005
Tongue
Chinese
Weight
469 KB
Volume
25
Category
Article
ISSN
0510-9752

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## Abstract ## Objective CD16 (IgG Fcฮณ receptor type IIIA [FcฮณRIIIA])โ€“expressing CD14+ monocytes express high levels of Tollโ€like receptor 2 (TLRโ€2) and are able to efficiently produce proinflammatory cytokines such as tumor necrosis factor ฮฑ (TNFฮฑ). To understand the role of CD16 and TLRโ€2 in mon