Tolerance to human gamma globulin in mice selected for high or low antibody responsiveness
β Scribed by Heumann, A.M.; Mouton, D.
- Book ID
- 122418330
- Publisher
- Elsevier Science
- Year
- 1983
- Weight
- 460 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0769-2625
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π SIMILAR VOLUMES
High (H/s) and low (L/s) antibody responder lines of mice selected according to their response to the somatic (s) antigen of Salmonella (Selection IV) have unexpected inverse capacity for antibody production to rabbit gamma globulin (RGG): H/s mice are low or even nonresponders to this antigen, wher
The effect of the selective breeding of mice for high or low antibody production to complex immunogens is largely "nonspecific", since it modifies the responsiveness of high (H) and low (L) lines to many antigens unrelated to the selection antigen. However, the nonspecific effect of the polygenic co