## Abstract ## Background Though tobramycin inhalation solution has been used for over a decade to improve lung function and reduce exacerbations in patients with cystic fibrosis (CF), its effects on mortality have not been wellโdescribed. This study aimed to assess the association between use of
Tobramycin dosage recommendation in patients with cystic fibrosis
โ Scribed by R. L. Davis; P. Mendelman; Bonnie Ramsey; A. L. Smith
- Publisher
- Springer-Verlag
- Year
- 1989
- Tongue
- English
- Weight
- 188 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0300-8126
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๐ SIMILAR VOLUMES
A recently developed tobramycin preparation for inhalation (TOBIเฎพ, Pathogenesis Corp., Seattle, WA) is widely used in CF patients. It is often used in conjunction with intravenous tobramycin. Renal and ototoxicity associated with the use of tobramycin require that serum drug concentrations be monito
The use of inhaled tobramycin for prophylaxis and treatment of respiratory symptoms in cystic fibrosis (CF) is now widespread. There have been concerns that inhaling the intravenous (I.V.) formulation of tobramycin causes bronchoconstriction. Previous studies using this formulation have either not s
To nine cystic fibrosis patients with chronic bronchopulmonary infection of severely damaged lungs invaded by Pseudomonas aeruginosa, eleven courses of prolonged tobramycin treatment (5 mg/kg/day) for four to 16 weeks were administered. Pulmonary symptoms improved and a better quality of life was ac