Amiodarone pharmacokinetics. II. Disposi
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Scott J. Weir; Clarence T. Ueda
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Article
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1987
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John Wiley and Sons
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English
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A 30 mg kg-' intravenous bolus of I4C-amiodarone (19 pCi kg-') was given to male Sprague-Dawley rats pretreated with 0 (vehicle), 25 or 100mgkg-' day-' of amiodarone HCI orally for 37-42 days to determine the effects of dose and duration of administration on the disposition kinetics of amiodarone. S