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TNF:TNF-R T-Cell costimulatory pathways in transplantation

โœ Scribed by A. Yamada; A.D. Salama; N. Najafian; H. Auchincloss Jr; M.H. Sayegh


Book ID
117231256
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
121 KB
Volume
33
Category
Article
ISSN
0041-1345

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The cytotoxic effects of TNF on malignant cells are known to be mediated through high affinity surface receptors. The precise mechanism by which transformed cells are selectively killed by the activation of these receptors is yet unknown, but several intracellular signaling pathways are known to be