Interferons have been used to treat chronic hepatitis owing to their antiviral properties. However, now interferons are recognized to inhibit collagen production. Because fibrosis has been associated with liver damage and disfunction, the effects of interferon-azh on biliary obstruction-induced cirr
✦ LIBER ✦
TNF-α and leptin in experimental liver fibrosis models induced by carbon tetrachloride and by common bile duct ligation
✍ Scribed by İbrahim Halil Bahçecıoğlu; Mehmet Yalniz; Hüseyin Ataseven; Nurullah Bülbüller; Muzaffer Keçecı; Kutbeddin Demırdağ; İbrahim Özercan; Bilal Üstündağ
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 194 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0263-6484
- DOI
- 10.1002/cbf.1114
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Interferon-␣ 2b (IFN) is known to prevent and to reverse experimental liver fibrosis and damage. S-Adenosyl-l-methionine (SAM) is a well-known hepatoprotective substance. The aim of the present work was to determine the effect of the administration of both drugs simultaneously to bile duct-ligated r