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TNF-α and IL-1β Suppress N-Cadherin Expression in MC3T3-E1 Cells

✍ Scribed by Takahiro Tsutsumimoto; Satoshi Kawasaki; Sohei Ebara; Kunio Takaoka

Book ID: 111486438
Publisher: American Society for Bone and Mineral Research
Year: 1999
Tongue: English
Weight: 639 KB
Volume: 14
Category: Article
ISSN: 0884-0431
DOI: 10.1359/jbmr.1999.14.10.1751

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## Abstract Thrombospondin 1 (TSP1) is a multifunctional extracellular glycoprotein present mainly in the fetal and adult skeleton. Although an inhibitory effect of TSP1 against pathological mineralization in cultured vascular pericytes has been shown, its involvement in physiological mineralizatio