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Enamel matrix derivative inhibits TNF-α–induced apoptosis in osteoblastic MC3T3-E1 cells

✍ Scribed by Jianing He; Yiming King; Jin Jiang; Kamran E. Safavi; Larz S.W. Spångberg; Qiang Zhu

Book ID: 116940803
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 527 KB
Volume: 99
Category: Article
ISSN: 1528-395X
DOI: 10.1016/j.tripleo.2004.07.022

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## Abstract Thrombospondin 1 (TSP1) is a multifunctional extracellular glycoprotein present mainly in the fetal and adult skeleton. Although an inhibitory effect of TSP1 against pathological mineralization in cultured vascular pericytes has been shown, its involvement in physiological mineralizatio