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TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells

✍ Scribed by Devang N. Patel; Steven R. Bailey; John K. Gresham; David B. Schuchman; James H. Shelhamer; Barry J. Goldstein; Brian M. Foxwell; Michael B. Stemerman; Jodi K. Maranchie; Anthony J. Valente; Srinivas Mummidi; Bysani Chandrasekar

Book ID: 116293301
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 852 KB
Volume: 347
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2006.07.015

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## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor