Cover Picture: Total Synthesis and Antit
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Ulrich Klar; Bernd Buchmann; Wolfgang Schwede; Werner Skuballa; Jens Hoffmann; R
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Article
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2006
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John Wiley and Sons
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English
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**__Nature is a brilliant architect__** for the design of compounds with interesting biological functions. Epothilone B (top), a metabolite of myxobacteria (fruiting body in background), served as the lead structure for the development of an anticancer drug candidate. Optimization efforts led to ZKโ