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Titanium(II)-Mediated Cyclizations of (Silyloxy)enynes: A Total Synthesis of (-)-7-Demethylpiericidin A1.

โœ Scribed by Katie A. Keaton; Andrew J. Phillips


Publisher
John Wiley and Sons
Year
2006
Weight
10 KB
Volume
37
Category
Article
ISSN
0931-7597

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An efficient synthesis of optically acti
โœ Yongcheng Song; Yuuki Takayama; Sentaro Okamoto; Fumie Sato ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 376 KB

Ti(II)-mediated cyclization of readily accessible optically active secondary 2,7-and 2,8-enyn-1-ol derivatives enables the selective preparation of any one of the four possible stereoisomers of the cyclized product with high optical purity.