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Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells

✍ Scribed by Mangala, L S; Fok, J Y; Zorrilla-Calancha, I R; Verma, A; Mehta, K

Book ID
110072040
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
450 KB
Volume
26
Category
Article
ISSN
0950-9232

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## Abstract Granzyme B (GrB) is a serine proteinase known to be expressed by cytotoxic lymphocytes and to induce, in presence of perforin (Pf), apoptosis in target cells. Recently, GrB expression has been shown (often in absence of Pf) in nonlymphoid cells, but its function is not defined. In our s