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Programmed Cell Death 4 inhibits breast cancer cell invasion by increasing Tissue Inhibitor of Metalloproteinases-2 expression

✍ Scribed by René Nieves-Alicea; Nancy H. Colburn; Ann-Marie Simeone; Ana M. Tari


Publisher
Springer US
Year
2008
Tongue
English
Weight
446 KB
Volume
114
Category
Article
ISSN
0167-6806

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## Abstract P450 aromatase catalyzes the conversion of androgens to estrogens and plays a key role in the cell growth of hormone‐dependent breast cancer in postmenopausal women. On the other hand, matrix metalloproteinases (MMPs), which can degrade almost all components of the extracellular matrix,