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Tissue-specific modulation of cyclooxygenase-2 (Cox-2) expression in the uterus and the v. cava by estrogens and phytoestrogens

✍ Scribed by T. Hertrampf; S. Schmidt; U. Laudenbach-Leschowsky; J. Seibel; P. Diel

Book ID: 116733761
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 328 KB
Volume: 243
Category: Article
ISSN: 0303-7207
DOI: 10.1016/j.mce.2005.08.007

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## Abstract Previous studies from our laboratory and others have suggested that increased expression of __cox‐2__ is important in the genesis of esophageal adenocarcinoma. __In vitro__ studies suggest that __cox‐2__ regulates expression of the anti‐apoptotic protein bcl‐2, thus possibly accounting