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Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene

โœ Scribed by GW Xu; ZT Sun; K Forrester; XW Wang; J Coursen; CC Harris

Book ID
118686470
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
647 KB
Volume
24
Category
Article
ISSN
0270-9139

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Tissue-specific growth suppression and c
Tissue-specific growth suppression and chemosensitivity promotion in human hepatocellular carcinoma cells by retroviral-mediated transfer of the wild-type p53 gene
โœ G W Xu; Z T Sun; K Forrester; X W Wang; J Coursen; C C Harris ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 646 KB

HCC patients are generally resistant to chemotherapy, Selective expression of cytotoxic gene products in tuwhich, in some cases, may be the result of a loss of function mor cells is one of the goals of gene therapy for treating mutation in the p53 gene. cancer. We are developing such a strategy for