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Tissue-specific expression of a BAC transgene targeted to the Hprt locus in mouse embryonic stem cells

✍ Scribed by Jason D. Heaney; Ashley N. Rettew; Sarah K. Bronson


Book ID
116981230
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
817 KB
Volume
83
Category
Article
ISSN
0888-7543

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Stem cells have the potential to be differentiated to a specific cell type through genetic manipulation and therefore, represent a new and versatile source of cell replacement in regenerative medicine. However, conventional ways of gene transfer to these progenitor cells, suffer from a number of dis