Tissue plasminogen activator for blocked peritoneal dialysis catheters
β Scribed by R. G. Krishnan; N. E. Moghal
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 74 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0931-041X
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## Abstract ## BACKGROUND The formation of a fibrin sheath thrombus is the most common cause of hemodialysis catheter dysfunction (HCD). The infusion of a lowβdose recombinant tissue plasminogen activator (rtPA) has been shown to be safe and effective. However, there is no consensus as to the opti
## Abstract An electrochemical assay for tissue plasminogen activator (tβPA) is described. The activity of tβPA is measured in a coupled assay following the amidolytic cleavage of a synthetic tripeptide by the enzyme plasmin. The released electroactive label, pβaminophenol, is detected anodically e