Positive correlation between P27Kip1 exp
โ
Takashi Anayama; Mutsuo Furihata; Tadanori Ishikawa; Yuji Ohtsuki; Shohei Ogoshi
๐
Article
๐
1998
๐
John Wiley and Sons
๐
French
โ 588 KB
p27 Kip1 , one of the cyclin-dependent kinase (CDK) inhibitors (CDKIs), blocks progression from G 1 to S phase by binding cyclin D1-CDK4 and/or cyclin E-CDK2 and inhibiting their activities. Reflecting the function of p27 as a CDKI in vitro, a reduced expression of protein p27 has recently been repo