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Tissue factor accelerates the activation of coagulation factor VII: The role of a bifunctional coagulation cofactor

✍ Scribed by Yale Nemerson; Doris Repke

Book ID
119035844
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
436 KB
Volume
40
Category
Article
ISSN
0049-3848

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To investigate the effect of tissue-type plasminogen activator (t-PA) on blood coagulation, we examined the effects of the addition of t-PA to normal pool plasma (NPP) on clotting times such as diluted prothrombin time (PT) and kaolin clotting time (KCT). The diluted PT but not the KCT was significa