Tissue distribution studies in rats with two 125I-labeled adrenal scanning agents. Comparison between 131I-6-Iodomethyl-19-norsitost-5(10)-en-3β-ol (NST-6-131I) and 19-iodositost-5-en-3β-ol (ST-19-3β-131I)

Synthesis of a new adrenal cortex imagin

Synthesis of a new adrenal cortex imaging agent 6β-131 I-iodomethyl-19-nor cholest -5(10)-en-3β-ol (NP-59)

✍ Garabed P. Basmadjian; Kenneth R. Hetzel; Rodney D. Ice; William H. Beierwaltes 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 250 KB

## Abstract A new adrenal cortex imaging agent. 6β‐^131^ I‐iodomethyl‐19‐norcholest‐5(10)‐en‐3β‐ol (NP‐59)[__I__] was synthesized by the homallylic rearrangement of 19‐iodocholesterol or directly from cholest‐5‐ene‐3β, 19‐diol‐19‐toluene‐p‐sulfonate via homoallylic rearrangement with the iodide ion