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Ti(salen)-catalyzed enantioselective sulfoxidation using hydrogen peroxide as a terminal oxidant

✍ Scribed by Bunnai Saito; Tsutomu Katsuki

Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
63 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis

R,R)-Di-m-oxo Ti(salen) 4 was found to serve as an efficient catalyst for asymmetric oxidation of various sulfides with hydrogen peroxide. For example, oxidation of methyl phenyl sulfide by using 4 as the catalyst in the presence of a ureaβ€’H 2 O 2 adduct showed high enantioselectivity of 94% ee. The high enantioselectivity of this reaction was considered to be related to the cis-b-structure of a monomeric Ti(salen) species generated from 4 in a methanol-hydrogen peroxide solution.

πŸ“œ SIMILAR VOLUMES

Cationic Co(III)(salen)-catalyzed enanti
Cationic Co(III)(salen)-catalyzed enantioselective Baeyer–Villiger oxidation of 3-arylcyclobutanones using hydrogen peroxide as a terminal oxidant
✍ Tatsuya Uchida; Tsutomu Katsuki πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 72 KB

A cationic Co(III)(salen) complex of cis-b-structure was found to serve as an efficient catalyst for asymmetric Baeyer-Villiger reaction of 3-substituted cyclobutanone using hydrogen peroxide as a terminal oxidant. Good enantioselectivity up to 78% ee was achieved.