Tissue inhibitor of metalloproteinase-1
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Ting Wang; Jing-Huan Lv; Xiong-Fei Zhang; Chao-Jun Li; Xiao Han; Yu-Jie Sun
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Article
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2010
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John Wiley and Sons
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French
โ 346 KB
## Abstract Paclitaxel (PTX) is a very effective drug in treating tumors. It disturbs microtubule dynamics and impairs the transition of cells from metaphase to anaphase in mitosis, leading to cell death by apoptosis. However, the effectiveness of PTX in cancer chemotherapy is hampered by drug resi