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Time resolved fluoroimmunoassay of 7-methyl-2′-deoxyguanosine imidazole (ring open)

✍ Scribed by Paolo Degan; Ruggero Montesano; Angelo Abbondandolo; Giorgio Montagnoli


Book ID
118901983
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
579 KB
Volume
133
Category
Article
ISSN
0022-1759

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The regiosetective ring-opening reaction of a-methyl-B-propiolactone with 3,3-ethytenedioxybutytmagnesiwn bromide in the presence of copper(I) cataZyst afforded 2-methyl-6-oxoheptanoic acid, which was easily converted into IEI-3,7-dimethyl-2-octene-I,&dial in good yield.