A novel synthesis of (E)-3,7-dimethyl-2-octene-1,8-diol secreted by the african monarch using the ring-opening reaction of α-methyl-β-propiolactone

✍ Scribed by Tamotsu Fujisawa; Toshio Sato; Tatsuo Kawara; Atsunari Noda

• Publisher: Elsevier Science
• Year: 1982
• Tongue: French
• Weight: 131 KB
• Volume: 23
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)88593-7

✦ Synopsis

The regiosetective ring-opening reaction of a-methyl-B-propiolactone with 3,3-ethytenedioxybutytmagnesiwn bromide in the presence of copper(I) cataZyst afforded 2-methyl-6-oxoheptanoic acid, which was easily converted into IEI-3,7-dimethyl-2-octene-I,&dial in good yield.