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Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells

✍ Scribed by Lorena Donnici; Ettore Tiraboschi; Daniela Tardito; Laura Musazzi; Giorgio Racagni; Maurizio Popoli

Book ID
115007533
Publisher
BioMed Central
Year
2008
Tongue
English
Weight
387 KB
Volume
9
Category
Article
ISSN
1471-2202

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Biphasic modulation of cell proliferatio
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✍ Gerlinde Pappa; Helmut Bartsch; Clarissa GerhΓ€user πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 697 KB

## Abstract Sulforaphane (SFN), a cancer chemopreventive compound derived from broccoli, is able to induce cell cycle arrest and apoptosis in various tumor cell lines. Here we show that cell growth inhibition by SFN follows a biphasic pattern: Transient exposure of 40‐16 human colon carcinoma cells