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Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans

✍ Scribed by Hester van der Woude; Anna Gliszczyńska-Świgło; Karin Struijs; Astrid Smeets; Gerrit M. Alink; Ivonne M.C.M. Rietjens


Book ID
117467919
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
137 KB
Volume
200
Category
Article
ISSN
0304-3835

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Biphasic modulation of cell proliferatio
✍ Gerlinde Pappa; Helmut Bartsch; Clarissa Gerhäuser 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 697 KB

## Abstract Sulforaphane (SFN), a cancer chemopreventive compound derived from broccoli, is able to induce cell cycle arrest and apoptosis in various tumor cell lines. Here we show that cell growth inhibition by SFN follows a biphasic pattern: Transient exposure of 40‐16 human colon carcinoma cells