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Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse

✍ Scribed by Marcia N. Gordon; Leigh A. Holcomb; Paul T. Jantzen; Giovanni DiCarlo; Donna Wilcock; Kristal W. Boyett; Karen Connor; Jason Melachrino; James P. O'Callaghan; Dave Morgan


Book ID
115607592
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
883 KB
Volume
173
Category
Article
ISSN
0014-4886

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## Abstract Alzheimer's disease (AD) is a progressive neurodegenerative disease associated with senile β‐amyloid (AΞ²) plaques and cognitive decline. Neurogenesis in the adult hippocampus is implicated in regulating learning and memory, and is increased in human postmortem brain of AD patients. Howe