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Thyrotropin-releasing hormone: central site of action in antagonism of pentobarbital narcosis

✍ Scribed by KALIVAS, P. W.; HORITA, A.


Book ID
109713539
Publisher
Nature Publishing Group
Year
1979
Tongue
English
Weight
367 KB
Volume
278
Category
Article
ISSN
0028-0836

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Failure of muscarinic blockade to antago
✍ Emily M. Santori; Dennis E. Schmidt; Peter W. Kalivas; Akira Horita πŸ“‚ Article πŸ“… 1981 πŸ› Springer 🌐 English βš– 391 KB

In the rat, the antimuscarinics atropine and scopolamine failed to block the reduction in pentobarbital-induced sleep time produced by either thyrotropin-releasing hormone (TRH) or MK-771 (a TRH analog). Previous reports have indicated that the marked analeptic effect produced by TRH is antagonized