✦ LIBER ✦

Thyroid-stimulating hormone levels after radiotherapy and combined therapy for head and neck cancer

✍ Scribed by Dr. Mark C. Weissler; Billy W. Berry

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 375 KB
Volume: 13
Category: Article
ISSN: 1043-3074
DOI: 10.1002/hed.2880130508

No coin nor oath required. For personal study only.

✦ Synopsis

Sixty

-eight patients were studied prospectively with serial thyroid-stimulating hormone (TSH) levels after radiotherapy for head and neck neoplasms. Overall, 57% of the patients developed elevated TSH levels. Excluding patients with less than 2 years follow-up, 85% developed an elevated TSH. Ninety-two percent of patients treated with partial thyroidectomy and radiotherapy developed an elevated TSH. Most TSH elevations occurred within 1 year of treatment. The dose of radiotherapy used and the performance of hemithyroidectomy were related to the development of elevated TSH levels (p < 0.05). The performance of radical neck dissection, gender, hyperfractionated radiotherapy, and the use of chemotherapy were not related to the development of an elevated TSH (p > 0.05).

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