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Thyroid hormone transporters in the brain

✍ Scribed by Takehiro Suzuki; Takaaki Abe


Book ID
107648206
Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
217 KB
Volume
7
Category
Article
ISSN
1473-4222

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Cellular thyroid hormone uptake and efflux are mediated by transmembrane transport proteins. One of these, monocarboxylate transporter 8 (MCT8) is mutated in Allan-Herndon-Dudley syndrome, a severe mental retardation associated with abnormal thyroid hormone constellations. Since mice deficient in Mc