Thymocyte activating factors from SV40-transformed human embryo fibroblasts
✍ Scribed by Yasuji Okai; Sadao Gotoh; Uki Yamashita
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 359 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0165-2478
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## Abstract Lowering of extracellular Ca^2+^ levels will reversibly arrest the growth of human fibroblasts (WI38). Simian virus~40~(SV~40~)‐transformed WI38 cells do not exhibit this Ca^2+^‐dependent arrest. One possibility for this difference in Ca^2+^ requirement is that extracellular or surface
## Abstract Membrane vesicles isolated from untransformed Balb/c and Swiss mouse fibroblasts and their SV 40‐transformed derivatives were shown to catalyze carrier‐mediated, intravesicular uptake of α‐aminoisobutyric acid and D‐glucose. Concentrative uptake of α‐aminoisobutyric acid required the pr