Heterogenous macrophage-activating factors from extracellular matrix of human embryo fibroblasts
โ Scribed by Yasuji Okai
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 321 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0165-2478
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๐ SIMILAR VOLUMES
Basic fibroblast growth factor (bFGF) binds to heparin-like molecules present in the extracellular matrix (ECM) of transformed fetal bovine aortic endothelial G M 7373 cells. Binding of bFGF to ECM can be competed by heparin or heparan sulfate, and ECM-bound bFGF can be released by treating the cell
## Abstract It is advantageous to use biomaterials in tissue engineering that stimulate extracellular matrix (ECM) production by the cellular component. Connective tissue growth factor (CTGF) stimulates type I collagen (__COL1A1__) transcription, but is functionally limited as a free molecule. Usin